Generic and brand - Arimidex
Anastrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.
Anastrozole is used to treat breast cancer in postmenopausal women. It is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox). Anastrozole may also be used for other purposes not listed in this medication guide.
Breast cancer has taken the shape of an epidemic among women, particularly postmenopausal women. There are several types of treatment available for breast cancer patients, namely surgery including mastectomy or lumpectomy, radiation therapy, drug-aided chemotherapy, hormone therapy consisting of tamoxifen, and the aromatase inhibitors like Arimidex (Anastrozole), Aromasin (Exemestane) and Femara (Letrozole). You can also rely on biological therapy such as Herceptin to treat this dreaded disease.
Hormonal therapy has gained popularity over the years as an adjuvant (post-surgery) treatment of early stage breast cancer in postmenopausal women. Tamoxifen was the most sought-after hormonal therapy available in the market until a number of aromatase inhibitors like Arimidex (Anastrozole) came into the picture. Various clinical trials have found these inhibitors quite superior to tamoxifen in terms of effectiveness.
Arimidex (Anastrozole) blocks the action an enzyme called aromatase which is responsible for the conversion of androgens to estrogens. Estrogen is a type of hormone that usually promotes the rapid increase in the number of breast cancer cells, remained in the body even after breast cancer surgery. Inhibiting the action of aromatase enzyme leads to reduced levels of estrogen in the blood. This, in return, hampers the growth of breast cancer cells in the body and keeps the disease under control.
Anastrozole under the brand name Arimidex is the active ingredient in this medication. It is orally administered in 1 mg tablet form. Each tablet comprises certain inactive ingredients such as lactose, hydroxypropylmethylcellulose, magnesium stearate, sodium starch glycolate, polyethylene glycol, povidone, and titanium dioxide.
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